Oxcarbazepine is used alone or in combination with other medications to control certain types of seizures. It is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain. It is a white to faintly orange crystalline powder. The Molecular Formula is C15H12N2O2, Molecular Weight is 252.27,and CAS NO is 28721-07-5. It is an anticonvulsant and mood-stabilizing drug, used primarily in the treatment of epilepsy.

In treatment of epilepsy, oxcarbazepine has recently been found to be associated with a greater enhancement in mood and reduction in anxiety symptoms than other drugs employed to treat epilepsy.It also appears to be effective in approximately half of patients with bipolar disorder and is well tolerated.Oxcarbazepine(CAS NO: 28721-07-5) is also sometimes used to treat bipolar disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of frenzied abnormal excitement, and other abnormal moods).

Oxcarbazepine comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours (twice a day) with or without food. Take oxcarbazepine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take oxcarbazepine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Oxcarbazepine may help control your seizures but will not cure your condition. Continue to take oxcarbazepine even if you feel well. Do not stop taking oxcarbazepine without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking oxcarbazepine, your seizures may get worse. Your doctor will probably decrease your dose gradually.

Take this medication by mouth, usually twice daily. This drug may be taken with or without food.The dosage is based on your medical condition (including pregnancy) and response to therapy.It is important to take all doses on time to keep the level of medication in your blood constant. Take doses at evenly spaced intervals. Do not skip doses. Do not suddenly stop taking Oxcarbazepine without your doctor's approval since seizures may reoccur.

Oxcarbazepine can cause dizziness, drowsiness, blurred or double vision, fatigue, and may cause headaches, nausea and vomiting. There is also evidence of difficulty in concentration and mental sluggishness. Oxcarbazepine can also cause hyponatremia (2.7% of patients), so blood sodium levels should be tested if the patient complains of severe fatigue.

Want to learn more information about Oxcarbazepine, you can access the guidechem.com.

 Benzenesulfonyl chloride a colorless to slightly yellow solid that melts at approximately 40 F. Very irritating to skin, eyes and mucous membranes. May emit toxic fumes when heated to high temperatures. Used to make dyes and other chemicals.

Benzenesulfonyl chloride may contain highly toxic and irritating hydrogen chloride and oxides of chlorine and sulfur. Cylinder may explode. Decomposes to produce highly toxic chlorine and sulfur compounds. Reacts with hot water to produce highly toxic and corrosive hydrochloric acid and benzenesulfonic acid.

Benzenesulfonyl chloride(CAS NO: 98-09-9) is incompatible with strong oxidizing agents and bases, including amines. Corrodes metals in the presence of water due to slow formation of hydrochloric acid and benzenesulfonic acid. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts.

You can buy Benzenesulfonyl chloride in guidechem, here are the supply information:

1.Wuhan Fortuna Chemical Co., Ltd.
Benzenesulfonyl chloride(CAS NO: 98-09-9)
Updatetime:Jan 10 2014
Purity:99%min Min. Order: Supply Ability:avaiable stock 
DetailDesc:Benzenesulfonyl chloride
Tel:0086-27-59207850
Address:A2705,Dong Yi Shi Qu,129 XinHua Road

2.Hangzhou Dayangchem Co., Ltd.
Updatetime:Jan 10 2014
DetailDesc:Benzenesulfochloride
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

3.Hui Chem Company Limited
Updatetime:Jan 09 2014
Purity:98% Min. Order:1/Gram Supply Ability:10 Month/Kilogram
DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale
Tel:86-21-60542966
Address:Lane 299 Bisheng Rd,Pudong District

4.Zhejiang Kaili Industrial Co., Ltd.
Updatetime:Jan 08 2014
DetailDesc:Zhejiang Kaili Industrial Co., Ltd. is collect Science, Industrial and Trade together for a comprehensive high-tech entities. We are mainly engaged in the research, development, production and sales of APIs and pharmaceutical intermediates.
Tel:86-571-85241926
Address:Block C&D,12/F,Lantian Business Center,No.18 Moganshan Road,Hangzhou,China

5.Hebei Rui Ning Import & Export Trading Co.,Ltd
Updatetime:Mar 14 2012
Purity:99.0%min
DetailDesc: Appearance - Clear liquid or straw yellow lucency liquid Purity 99.0%min Free Acid 0.2%max Water 0.5%max Colority(APHA) 50 Pt/Co max
Tel:86-311-89648859
Address:East Wing 1705 Business Building of Xinhua, Shi Jia Zhuang, China

6.Suzhou (Jiangsu Province) Best Fine Chemicals Group Co., Ltd
Benzenesulfonyl chloride
Updatetime:Dec 18 2010
Tel:0086-512-65352871 65331158
Address:46, Ziyou Rd., Xizhan, Baiyangwan, Suzhou City, Jiangsu Prov., China.

7.Zouping Mingxing Chemical Co.,Ltd.
Benzenesulfonyl chloride
Updatetime:Jul 19 2013
Purity:99
DetailDesc: benzenesulfonyl chloride English name Benzenesulfonyl chloride Chinese alias chlorinated benzene sulfonyl; BSC; benzene sulfonyl chloride CAS RN 98-09-9 EINECS No. 202-636-6 Molecular formula C6H5ClO2S Molecular Weight 176.6207 Properties transparent colorless oily liquid. 
Tel:86-135-15431451
Address:428 Daixi Third Road Zouping County Shandong Province China

Want to learn more information about Benzenesulfonyl chloride, you can access the guidechem.com. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

 Ranolazine is a medication that belongs to the drug class known as cardiovascular agents. Ranolazine is used alone or with other medications to treat ongoing angina (chest pain or pressure that is felt when the heart does not get enough oxygen).It works by improving blood flow to help the heart work more efficiently. It is used to treat chronic angina (chest pain). But it is not for use during an acute (emergency) attack of angina. Ranolazine(CAS NO:95635-55-5) may also be used for purposes not listed in this medication guide.

On 24 April 2008, the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing authorisation for the medicinal product Latixa, 375-mg, 500-mg and 750-mg, prolonged-release tablets intended for treatment of patients with stable angina pectoris. The applicant for this medicinal product is CV Therapeutics Europe Limited.

The Food and Drug Administration has approved a new, first-line indication for ranolazine for the treatment of chronic angina. The new labeling also provides information showing ranolazine(CAS NO:95635-55-5)reduced arrhythmias, including ventricular arrhythmias, new onset atrial fibrillation and a potentially dangerous slow heartbeat known as bradycardia in patients with coronary artery disease.

A total of 2,018 patients with chronic angina were treated with ranolazine in controlled clinical trials. Of the patients treated with Ranolazine, 1,026 were enrolled in three double-blind, placebocontrolled, randomized studies (CARISA, ERICA, MARISA) of up to 12 weeks' duration. In addition, upon study completion, 1,251 patients received treatment with Ranolazine in open-label, long-term studies; 1,227 patients were exposed to RANEXA for more than 1 year, 613 patients for more than 2 years, 531 patients for more than 3 years, and 326 patients for more than 4 years.

Earlier, ranolazine increasing QT interval (about 2 to 6 ms) was of concern, which has a theoretical risk of causing arrhythmia. Findings of MERLIN TIMI 36 should mitigate this concern. However, studies specifically designed to evaluate the potential role of ranolazine as an antiarrhythmic agent are warranted.

You can find high quality Ranolazine in Guidechem, here are some lastes information about Ranolazine in Guidechem.

1.Wuhan Fortuna Chemical Co., Ltd.
Ranolazine
Updatetime:Jan 09 2014
Purity:99% Min. Order:1/5/25/Kilogram
Tel:0086-27-59207850
Address:A2705,Dong Yi Shi Qu,129# XinHua Road

2.Capot Chemical Co., Ltd.
Ranolazine
Updatetime:Jan 09 2014
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:427.54,C24H33N3O4
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

3.AFINE CHEMICALS LIMITED
Ranolazine 
Updatetime:Jan 07 2014
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:Ranolazine 95635-55-5
Tel:86-571-85232161
Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

There are large number of manufacturers, suppliers, exporters, importers, buyers, wholesalers, producers in Guidechem, if you need more information about Ranolazine, you can access the guidechem.com. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

 Firstly, let’s me show you suppliers who can provide high quality 2-Chloro-5-iodopyridine, these suppliers are in Guidechem.

1.Shanghai Dell Chemical Co.Ltd
Updatetime:Jan 06 2014
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

2.Capot Chemical Co., Ltd.
2-Chloro-5-iodopyridine(CAS NO:69045-79-0)
Updatetime:Jan 06 2014
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:239.44,C5H3ClIN
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

3.Jinan Haohua Industry Co., Ltd.
Updatetime:Jan 08 2014
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc: CAS Registry Number:69045-79-0, 2-chloro-5-iodo-pyridine;2-chloro-5-iodopyridine 98% 2g;2-chloro-5-iodopyrazine;
Tel:0086-531-58773055
Address:No.59 Gongye South RD

4.Hui Chem Company Limited
Updatetime:Jan 06 2014
Purity:98% Min. Order:1/Gram Supply Ability:10 Month/Kilogram
DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale
Tel:86-21-60542966
Address:Lane 299 Bisheng Rd,Pudong District

Then, I list the Precautions of 2-Chloro-5-iodopyridine for you, it is good for you to know the propeties about the chemicals, if you often contact them.

1.First aid measures

Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention.
Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothesand shoes. Obtain medical attention.
Ingestion: Clean mouth with water. Get medical attention.
Inhalation: Remove from exposure, lie down. Move to fresh air. If breathing is difficult, give oxygen. If notbreathing, give artificial respiration. Obtain medical attention.

2.Fire fighting measures

Suitable Extinguishing Media: Water spray. Carbon dioxide (CO2). Dry chemical. chemical foam.
Extinguishing media which must not be used for safety reasons: No information available.
Special hazards arising from the substance or mixture: Thermal decomposition can lead to release of irritating gases and vapors
Advice for fire-fighters: As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

3.Precautions for Safe Handling

Avoid contact with skin and eyes. Do not breathe dust. Do not breathe vapors or spray mist. Conditions for safe storage, including any incompatibilities Keep in a dry, cool and well-ventilated place. Keep container tightly closed. Keep away from direct sunlight.

4.Exposure and biological limits

2-Chloro-5-iodopyridine, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. 2-Chloro-5-iodopyridine, as supplied, does not contain any hazardous materials with established by the region specific regulatory bodies.

Want to learn more supply information about 2-Chloro-5-iodopyridine or any other chemicals, you can access the guidechem.com.Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.

Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, buckthorn and Japanese knotweed. It is a natural chemical supplement--called an anthraquinone--that is extracted from the root of the Turkish rhubarb plant. The Molecular Formula is C15H10O5, the Molecular Weight is 270.24, and the CAS Registry Number is 518-82-1.

The safety and effectiveness of this naturopathic treatment has not been approved by the U.S. Food and Drug Administration. It may help reduce inflammation and has been shown to destroy certain types of cancer cells. 

This natural supplement may be helpful in the treatment of specific medical conditions, including cancer, constipation, inflammation, microbial infections or peptic ulcers, explains the Memorial Sloan-Kettering Cancer Center in New York City. Before beginning treatment, talk with a doctor about potential emodin side effects.

Here are some questiones about Emodin(CAS NO: 518-82-1), I hope it may helpful for you!

1.What is Emodin and does it fight cancer?

Emodin is a product naturally produced in carrots. It can kill lung,liver and pancreatic cancer cells. It demonstrates anti-neoplastic, anti-inflammatory, anti-angiogenesis, and toxicological potential for use in pharmacology, both in vitro and in vivo. Emodin demonstrates cytotoxic effects (e.g., cell death) through the arrest of the cell cycle and the induction of apoptosis in cancer cells.

2.Alternative cancer treatments and scientific research on ?

There may be some benefits which is exactly why MD Anderson and Sloan Kettering are doing the research to see if the claims can be proven with REAL scientific data and research . So far the research has been less than spectacular and hardly the stand up proclaimation for a cure, still research continues so that if any benefit actually exists on some types of cancers than it can be used for treatments. There are over 200 different types of cancer and just as many subtypes, it is possible that some of these alt treatments may benefit some people or some stages of the disease hardly call any of them a 'cure' for cancer though. 

As for food, remember that cancer is your own unique DNA, your own cells, it isn't something foreign in the body. The food we eat supposedly is to make our bodies strong, there is evidence that some foods that we eat not only make the body strong but will strengthen and encourage the cancer to grow as well. This is why doctors encourage people who use alternatives to tell them which treatments they are using in some cases the alternatives intetere with the traditional cancer treatments and unfortunately in some cases actually promote cancer growth. 

I have know many cancer patients the majority of them with advanced cancer and unfortunately most have died. When people are dealing with a rare cancer with few treatment options they will often 'try out' the alternative medicine, so I have known quite a few who have done this. Out of at least 200 patients with advanced sarcoma, only the patients who went with traditional medicine have survived more than five years . I don't anyone who tried the alternative route who survived. That has been my observation.

3.Emodin - the affect on multiple myeloma cancer?

It's cancer of the plasma cells, which is found in bone marrow. It's called multiple because it tends to "clump" in multiple locations.

4.What is Emodin and its effect on cancer ?

If it ever comes to fruition, it would be a positive step in cancer treatments. Right now, Emodin is not being tested in actual humans or even animals yet. Many things tested work great in a petri dish, but less than positive outcomes in human trials. Some chemo drugs come from plants already, so keep your fingers crossed!

Want to learn more information about Emodin, you can access the guidechem.com. 

 Physical and chemical properties

Formula: C4H3BrS
Formula weight : 63.03
Synonyms:3-Thienyl bromide; beta-Bromo3-Bromothiophene;
Melting point < -10 C
Boiling point: 157 - 158 C
Specific gravity : 1.72 - 1.74
Solubility in water: immiscible 
Refractive index: 1.5863
Flash point:56 C
Stability Stable: under ordinary conditions
EINECS NO.: 212-821-3
CAS NO. : 872-31-1 
Appearance:3-Bromo3-Bromothiophene is clear to pale yellow liquid

Section MSDS information about 3-Bromothiophene

1.Fire Fighting Measures 
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. 
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.

2.Accidental Release Measures 
General Information: Use proper personal protective equipment as indicated. 
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.

3.Handling and Storage
Handling: Avoid breathing dust, mist, or vapor. Avoid contact with skin and eyes. 
Storage: Store in a cool, dry place. Store in a tightly closed container.

Usages and preparation

3-Bromothiophene(CAS NO: 872-31-1) is used as a solvent and chemical intermediate. Its derivatives are used in manufacturing dyes, aroma compounds and pharmaceuticals. They are used as monomers to make condensation copolymers. Organic conductive polymers are responsible for the important materials science for the application of polymer electro luminescence.

In commercial 3-Bromothiophene can be prepared by the reaction of butane and sulfur. 3-Bromothiophenes are also prepared by the reaction of diketones with Lawesson's reagent. This chemical and its derivatives exist in petroleum or coal. It derivatives are also found in natural plant pigments.

Supply information of 3-Bromothiophene

1.Capot Chemical Co., Ltd.
Updatetime:Dec 31 2013
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:163.03,C4H3BrS
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

2.Jinan Haohua Industry Co., Ltd.
Updatetime:Jan 06 2014
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:beta-Bromothiophene;3-Thienylbromide;.beta.-Bromothiophene;3-bromo thiophene;3-Bromothiophene Anhydrous;
Tel:0086-531-58773055
Address:No.59 Gongye South RD

3.HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD
3-Bromothiophene
Updatetime:Jan 06 2014
Supply Ability:Success 
DetailDesc:3-Bromothiophene
Tel:86-311-80955068
Address:No 98 Gongnong Street,Shijiazhuang Hebei,China

4.Hui Chem Company Limited
3-Bromothiophene
Updatetime:Jan 05 2014
Purity:98% Min. Order:1/Gram Supply Ability:10 Month/Kilogram
DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale
Tel:86-21-60542966
Address:Lane 299 Bisheng Rd,Pudong District

Want to learn more information about 3-Bromothiophene or any other chemicals, you can access the guidechem.com. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

 An efficient procedure for the trimethylsilylation of alcohols and phenols is presented. The combination of hexamethyldisilazane and a catalytic amount of phenyltrimethylammonium tribromide was found to be effective for the trimethylsilylation of alcohols and phenols. The protection reaction is very simple and homogenously performed in dichloromethane at room temperature and mild conditions.

An efficient method for the trimethylsilylation of alcohols and phenols using hexamethyldisilazane in the presence of catalytic amounts of phenyltrimethylammonium tribromide in CH2Cl2 at room temperature is reported.

Hexamethyldisilazane(CAS NO:999-97-3) is widely used as a silylating agent and is referred to as the "work horse" of the photoresist industry. This compound has a number of laboratory applications including the analytical determination of carbohydrates and acids, preparation of tissues for scanning electron microscopy, and derivation of mephentermine, mexiletine, and 2,4-dichlorophenoxy acetic acid. In addition, hexamethyldisilazane is used medicinally as an intermediate in the production of antibodies and anticancer drugs.

Here I will show you some suppliers of Hexamethyldisilazane, I hope this article will give some help to someone who need this chemicals.

1.Hangzhou Dayangchem Co., Ltd.
Updatetime:Jan 06 2014
DetailDesc:Hexamethyldisilylamine
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

2.HUTONG GLOBAL CO.,LTD
Hexamethyldisilazane(CAS NO:999-97-3)
Updatetime:Jan 05 2014
Purity:99% Min. Order:10/Metric Ton Supply Ability:1000 Month/Metric Ton
DetailDesc: Hexamethyldisilazane, HMDS 1. CAS No.: 999-97-3 2. Purity: 99% 3. Used as hydrophobing agent for filler Chemical Name: Silane coupling agent Hexamethyldisilazane, HMDS Synonym: 1,1,1,3,3,3-Hexamethyldisilazane; Bis(trimethylsilyl)amine 1. Properties: CAS No.: 999-97-3 .
Tel:86-22-59853797
Address:chagugang,wuqing district,Tianjin,China

3.Capot Chemical Co., Ltd.
Updatetime:Dec 31 2013
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:161.39,C6H19NSi2
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road,

4.HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD
Updatetime:Jan 06 2014
Supply Ability:Success 
DetailDesc:Hexamethyldisilylamine
Tel:86-311-80955068
Address:No 98 Gongnong Street,Shijiazhuang Hebei,China

5.Shanghai UCHEM Inc.
Updatetime:Jan 04 2014
DetailDesc:Hexamethyldisilazane
Tel:086-021-61555264
Address:4th Floor,Build A,500Jianyun Road,Zhoupu,Pudong,Shanghai

6.Amadis Chemical Co.,Ltd.
Updatetime:Jan 03 2014
DetailDesc:Pharmaceutical Intermediates
Tel:86-571-89925085
Address:SaiBo Pioneer Park.No.168,Jianding Road,Jianggan District.

7.Shijiazhuang Sdyano Fine Chemical Co., Ltd
Hexamethyldisilazane
Updatetime:Jan 06 2014
DetailDesc:Hexamethyldisilazane
Tel:86-311-89830448
Address:Room 37-2-2501, Yiyuan Dong Gang Jianshe Nan Stree

8.Nanjing Chemlin Chemical Co., Ltd.
Hexamethyldisilazane
Updatetime:Jan 02 2014
Purity:99%
DetailDesc:Hexamethyldisilazane
Tel:86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

Want to learn more information about Hexamethyldisilazane, you can access the guidechem.com. Guidechem Chemical Network providing the most complete information of the chemical industry.

Piperine, an organic compound classed either with the lipid family (a group consisting of fats and fatlike substances) or with the alkaloids, a family of nitrogenous compounds with marked physiological properties. It is one of the sharp-tasting constituents of the fruit of the pepper vine (Piper nigrum).

Piperine(CAS NO: 94-62-2) constitutes approximately 5 to 9 percent of commercial black or white pepper. It was first isolated in 1820, and its chemical constitution was established by laboratory syntheses in 1882 and 1894.

The sharp flavour of freshly ground pepper is attributed to the compound chavicine, a geometric isomer (having the same molecular formula but differing in structure) of piperine. The loss of pungency of ground pepper on storage is associated with slow transformation of chavicine into piperine.

Black pepper is one of the most widely used among spices. It is valued for its distinct biting quality attributed to the alkaloid, piperine(CAS NO: 94-62-2). Black pepper is used not only in human dietaries but also for a variety of other purposes such as medicinal, as a preservative, and in perfumery. 

Many physiological effects of black pepper, its extracts, or its major active principle, piperine, have been reported in recent decades. Dietary piperine, by favorably stimulating the digestive enzymes of pancreas, enhances the digestive capacity and significantly reduces the gastrointestinal food transit time. 

Piperine has been demonstrated in in vitro studies to protect against oxidative damage by inhibiting or quenching free radicals and reactive oxygen species. Black pepper or piperine treatment has also been evidenced to lower lipid peroxidation in vivo and beneficially influence cellular thiol status, antioxidant molecules and antioxidant enzymes in a number of experimental situations of oxidative stress. 

The most far-reaching attribute of piperine has been its inhibitory influence on enzymatic drug biotransforming reactions in the liver. It strongly inhibits hepatic and intestinal aryl hydrocarbon hydroxylase and UDP-glucuronyl transferase. Piperine has been documented to enhance the bioavailability of a number of therapeutic drugs as well as phytochemicals by this very property. 

Piperine's bioavailability enhancing property is also partly attributed to increased absorption as a result of its effect on the ultrastructure of intestinal brush border. Although initially there were a few controversial reports regarding its safety as a food additive, such evidence has been questionable, and later studies have established the safety of black pepper or its active principle, piperine, in several animal studies. Piperine, while it is non-genotoxic, has in fact been found to possess anti-mutagenic and anti-tumor influences.

Want to learn more information about Piperine, you can access the guidechem.com. 

 Cephalexin is a cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and bone, ear, skin, and urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections. Cephalexin is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Cephalexin is an antibiotic that belongs to the family of medications known as cephalosporins. It is used to treat certain types of bacteria infections. Cephalexin(CAS NO: 15686-71-2) is most often used to treat infections of the throat, skin, ear, bladder, respiratory tract, and bone. It works by killing the bacteria causing the infection.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Cephalexin(CAS NO: 15686-71-2), speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

Cefalexin is used to treat a number of infections including: otitis media, streptococcal pharyngitis, bone and joint infections, pneumonia, cellulitis, and urinary tract infections. It may be used to prevent bacterial endocarditis. Cefalexin as an important medicine, it also has some side effects, here I will give you some advice about the side effects of Cefalexin

Get emergency medical help if you have any of these signs of an allergic reaction to cephalexin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:
diarrhea that is watery or bloody;
seizure (convulsions);
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
pale or yellowed skin, dark colored urine, fever, confusion or weakness;
easy bruising or bleeding, unusual weakness;
confusion, agitation, hallucinations (seeing things that are not there); or
urinating less than usual or not at all.

Less serious cephalexin side effects may include:
mild nausea, vomiting, diarrhea;
dizziness, tired feeling;
joint pain; or vaginal itching or discharge.

The side effects may not the complete information about cephalexin, Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Want to learn more information about cephalexin, you can access the guidechem.com. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.

With the CAS registry number 4498-67-3, the IUPAC name of Indazole-3-carboxylic acid is 1H-indazole-3-carboxylic acid. Indazole-3-carboxylic acid is used in organic synthesis. For example: it can react with 1,4-dimethyl-[1,4]diazepan-6-ylamine to get 1H-indazole-3-carboxylic acid.This reaction needs reagent 1-ethyl-3-3-(dimethylamino)propyl carbodiimide hydrochloride and solvent CH2Cl2 at ambient temperature. The reaction time is 5 hours. The yield is 21%.

You can buy Indazole-3-carboxylic acid(CAS NO:4498-67-3) in our guidechem, now I will show some suppliers of Indazole-3-carboxylic acid in guidechem.

1.Hangzhou Dayangchem Co., Ltd.

Updatetime:Dec 31 2013

DetailDesc:Indazole-3-carboxylic acid

Tel:86-571-88938639

Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

2.Capot Chemical Co., Ltd.

Updatetime:Dec 31 2013

Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram

DetailDesc:162.15,C8H6N2O2

Tel:86-571-85586718

Address:Joinhands Science Park, No.4028,Nanhuan Road,

3.Wuhan Haizheng Industry & Trade Development Co. Ltd

Indazole-3-carboxylic acid(CAS NO:4498-67-3)

Updatetime:Dec 23 2013

Purity:98% Min. Order:10/Gram Supply Ability:1000 Year/Metric Ton

DetailDesc:EINECS: 224-794-5 Molecular Formula: C8H6N2O2 CAS Registry Number: 4498-67-3 

Tel:86-27-88660577

Address:27th FL.shuian international masion Bldg.1,Heping Ave.wuhan city

4.Aopharm 

Indazole-3-carboxylic acid

Updatetime:Dec 31 2013

Purity:99%

DetailDesc:yellow crystal

Tel:86-311-66600578

Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

5.Atomax Chemicals Co.,Ltd

Updatetime:Dec 11 2013

Purity:95%+ Min. Order:mg/g/Gram Supply Ability:kg/T Month/Kilogram

DetailDesc:We are a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. Those chemicals are widely used in the pharmaceutical and fine chemical industries and in research laboratories.

Tel:86-755-33239182

Address:Huiji302 Hutingju Sanwei Xixiang SHENZHEN 518126, China

6.China Huanyu Chemical Industrial Co.,Ltd

Updatetime:Dec 31 2013

DetailDesc:Indazole-3-carboxylic acid

Tel:86-310-6034055

Address:Maoyi Road,Hanshan District,Handan

7.Ningbo Sialon Chem Co., Ltd.

Updatetime:Dec 30 2013

Purity:0.99 Min. Order:10 Kilogram/Kilogram Supply Ability:100Kilogram Month/Metric Ton

DetailDesc:White crystal powder

Tel:+86-574-28809708

Address:Changle Village, Gaoqiao Town, Yinzhou District, Ningbo City, Zhejang Province, China(CN) .

8.Shijiazhuang Kaizheng Trading Co.,Ltd

Indazole-3-carboxylic Acid

Updatetime:Dec 30 2013

DetailDesc: best packing , shipping and will offer you our most competitive price . keep you good quality . hope you can come back to us . welcome you inquiry to us .

Tel:86-311-67503938

Address:1-1-818 lemo building,No.18 north of Pingan street,Qiaodong district,Shiajiazhuang

9.Boc Sciences

Indazole-3-carboxylic acid

Updatetime:Dec 20 2013

DetailDesc:Indazole-3-carboxylic acid

Tel:1-631-5046093

Address:45-16 Ramsey Road Shirley, NY 11967, USA

10.Shijiazhuang Sdyano Fine Chemical Co., Ltd

Indazole-3-carboxylic acid

Updatetime:Dec 31 2013

DetailDesc:Shijiazhuang Sdyano Fine Chemical Co., Ltd. is a company specializing in pharmaceutical intermediates, liquid crystal intermediates, PDLC LCD, OLED LCD, such as fine chemicals R & D, production and sales of integrated chemical enterprise modernization.

Tel:86-311-89830448

Address:Room 37-2-2501, Yiyuan Dong Gang Jianshe Nan Stree

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