What do you know about the usages of Ampicillin?
What is Ampicillin? Actually, Ampicillin is an antibiotic in the penicillin group of drugs. It fights bacteria in your body. It is a kind of Crystalline Solid,with the Molecular Formula:C16H19N3O4S and Molecular Weight:349.4. It is stable, but may be moisture sensitive,incopmpatible with strong oxidizing agents. Ampicillin is used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. The CAS Registry Number is 69-53-4.
We know Ampicillin is mainly used as a medicine, but what diseases can Ampicillin cure ?
An ampicillin resistance gene is commonly used as a selectable marker in routine biotechnology. Due to concerns over horizontal gene transfer to pathogenic organisms in the wild, the European Food Safety Authority restricts use of this gene in commercial genetically modified organisms. The enzyme responsible for degrading ampicillin is called beta-lactamase, in reference to the beta-lactam structure of ampicillin and related drugs.
Ampicillin(CAS NO:69-53-4) is closely related to amoxicillin, another type of penicillin, and both are used to treat urinary tract infections, otitis media, H. influenzae infection, salmonellosis, and Listeria meningitis.
It is used with flucloxacillin in the combination antibiotic co-fluampicil for empiric treatment of cellulitis, providing cover against group A streptococcal infection whilst the flucloxacillin acts against Staphylococcus aureus. Of concern is the number of bacteria that have become resistant to ampicillin, necessitating combination therapy or use of other antibiotics.
All Pseudomonas species and most strains of Klebsiella and Aerobacter are considered resistant. Additionally, resistance to ampicillin is seen in enterobacter, citrobacter, serratia, indole-positive proteus species, and other hospital-acquired gram negative infections.
Ampicillin has been used extensively to treat bacterial infections since 1961. Until the introduction of ampicillin by the British company Beecham, penicillin therapies had only been effective against Gram-positive organisms such as staphylococci and streptococci.
Ampicillin also demonstrated activity against Gram-negative organisms such as H. influenzae, coliforms and Proteus spp. Ampicillin was the first of a number of so-called broad-spectrum penicillins subsequently introduced by Beecham.
Ampicillin comes as a capsule, liquid, and pediatric drops to take by mouth. It is usually taken every 6 hours (four times a day). Shake the liquid and pediatric drops well before each use to mix the medication evenly. Use the bottle dropper to measure the dose of pediatric drops. The pediatric drops and liquid may be placed on a child's tongue or added to formula, milk, fruit juice, water, ginger ale, or other cold liquid and taken immediately.
If you need take Ampicillin, you should pay more attention to it. Learning more health information, properties or suppliers about Ampicillin, you can access Guidechem.